| Date |
Opponent |
Player of the Week |
Key Stats |
| Sept. 10 |
NY JETS |
LeSean McCoy |
110 yards rushing and 49 yards receiving |
| Sept. 17 |
at Carolina |
Jordan Poyer |
11 tackles, sack, 2 end zone pass breakups |
| Sept. 24 |
DENVER |
Stephen Hauschka |
Hit all 4 FGs from 49, 55, 53, and 27 yards |
| Oct. 1 |
at Atlanta |
Stephen Hauschka |
Hit all 3 FGs from 24, 56, and 55 yards |
| Oct. 8 |
at Cincinnati |
Brandon Tate |
TD reception, 40 yard punt return |
| Oct. 22 |
TAMPA BAY |
Deonte Thompson |
4 catches, 107 yards after signing during the week |
| Oct. 29 |
OAKLAND |
Matt Milano |
Fumble return for TD, forced fumble results in FG |
| Nov. 2 |
at NY Jets |
Zay Jones |
6 catches, 53 yards, 1 TD |
| Nov. 12 |
NEW ORLEANS |
None |
Bills got annihilated 47-10 |
| Nov. 19 |
at L.A. Chargers |
LeSean McCoy |
13 carries, 114 yards, 2 TDs |
| Nov. 26 |
at Kansas City |
Tre'Davious White |
Game clinching interceptions |
| Dec. 3 |
NEW ENGLAND |
Aldophus Washingto |
6 tackles, 2 sacks, 2 tackles for loss |
| Dec. 10 |
INDIANAPOLIS |
LeSean McCoy |
156 yards rushing, Game winning TD in OT |
| Dec. 17 |
MIAMI |
LeSean McCoy |
96 total yards, 2 TDs |
| Dec. 24 |
at New England |
LeSean McCoy |
71 yards rushing, 76 yards receiving |
| Dec. 31 |
at Miami |
Sean McDermott |
The rookie head coach ended the playoff drought |
| Jan 7* |
at Jacksonville |
Lorenzo Alexander |
10 tackles, sack, 2 tackles for loss |